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Namely, this basic link may be logical since in the stomach the cytoprotection (7, 8) maintains the endothelium for mucosal integrity, recognizes the lesion of the endothelium before the mucosal damage and endothelium protection to prevent the mucosal lesions development (4-6)

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1,4 SUSTAIN 5: add-on basal insulin 1,10 In adult patients with type 2 diabetes on basal insulin metformin Mean change in A1C from baseline at Week 30 Patients with A1C 8% at screening had their background basal insulin dose reduced by 20% at the start of the trial to limit the potential risk of hypoglycemia