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Although the binding of IgG via its Fc region renders it unable to bind the Fc receptor on circulating effector cells, the exact orientation/function of complement component C3 binding is not known ( Figure 2C )

Tetramethylpyrazine prevents contrast-induced nephropathy via modulating tubular cell mitophagy and suppressing mitochondrial fragmentation, CCL2/CCR2-mediated inflammation, and intestinal injury

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Ferroptotic pores induce Ca(2+) fluxes and ESCRT-III activation to modulate cell death kinetics