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Global, regional, and national burden of osteoarthritis, 1990-2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

[Abstract]2021 Oct;14(10):101167

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A separate meta-analysis that pooled results of trials in older adults with mild cognitive impairment found B-vitamin supplementation (6 to 24 months, depending on the trial) had no benefits on various cognitive parameters, including executive function, information processing speed, and episodic memory (90)

This review aims to outline the relevant mechanisms of ferroptosis, its implications in the bone microenvironment, and the mechanisms of action and therapeutic perspectives of ferroptosis in common bone and joint diseases, with the goal of informing future clinical research and treatment strategies targeting ferroptosis under these conditions