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In a small clinical trial of 25 adolescents, Arbaclofen has been found to rescue slow auditory sensory processing in males with idiopathic ASD [127]

The primary endpoint for the EMA was the percentage of patients achieving a SALT 10 at week 24, and the key secondary endpoint was improvement in the Patient's Global Impression of Change (PGI-C), defined as a rating of moderately improved or much improved at week 24 (PGI-C: a 7-point patient scale ranging from very much improved to very much worse).8 Baseline demographic and disease characteristics were balanced among treatment groups: 15% of patients were adolescents, 62% were women, 68% were White, and 46% had AT or AU

Frstermann, U., Xia, N

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