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Opting for lower-intensity workouts or exercising in cooler temperatures can help minimize the risk of a flare-up

This triggers downstream signaling pathways (e.g., NF-B and MAPK), driving the massive release of pro-inflammatory cytokines, including IL-1, IL-6, and TNF- (167170)

Homeoprotein signaling in the developing and adult nervous system

Frye and collaborators conducted a study on 48 non-syndromic ASD children with language impairment, diagnosed using ADOS, ADI-R or multidisciplinary clinical criteria