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Power analysis and advanced statistics can potentially help to reduce the number of replicates ( While pseudo-replication due to the re-use of animals can be compensated for using Bayesian statistics ( Pagurus bernhardus ( The number of replicates should then be carefully decided based on such previous experiments with the chosen model organisms
2.5 Apparatus and parameters 2.5.1 LC-QTOF-MS/MS The parameters of LC-QTOF-MS/MS methods depended on the equipment on which the analyses were carried out
In genetically susceptible individuals or those with prior toxicant exposure or infections, mast cells may become hyper-reactive, leading to a feed-forward loop of immune activation and tissue damage
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