Adolescents should be questioned about the chronic marijuana use to identify a condition termed cannabinoid hyperemesis syndrome (CHS) which is characterized by severe cyclical nausea, vomiting, and abdominal pain that are relieved by compulsive long hot water bathing ( Natural History/Prognosis CVS resolves, in most children (5070%) in late childhood or early adolescence ( Resolution of symptoms did not correlate with duration or severity of the disorder at presentation or with any of the other variables analyzed (sex, age at diagnosis, admission to the hospital, identification of trigger factors, travel sickness, family history of migraine) ( According to another study on 28 cases (adult and children) with CVS, 62% of patients showed a gradual improvement in symptoms and 24% had complete resolution after a mean of 7 years ( Many children with CVS stop having emetic episodes as they grow older, although they develop headache throughout clinical history
Receptor-mediated transcytosis of macromolecules across the blood-brain barrier
These reactions are usually transient and often decrease with continued administration
Melzer-Lange M, Walsh-Kelly C
In peptide therapy, GLP-1 analogs are used to mimic the effects of this hormone, leading to several weight loss benefits: Appetite Suppression: GLP-1 helps reduce hunger by signalling the brain to feel full
