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Individuals with malabsorption conditions, severe deficiency, or those who havent responded to oral supplements typically benefit most from injections

Because these surgeries bypass the part of the gut where absorption happens, the American Society for Metabolic and Bariatric Surgery notes that lifelong injections are often required

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Further Reading For additional peer-reviewed research, see: NNMT inhibitor preclinical study by Neelakantan et al

Importance of both folic acid and vitamin B12 in reduction of risk of vascular disease