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Vitamin B12 deficiency is common, particularly among people who follow vegetarian or vegan diets, as the vitamin is naturally found only in animal-based foods

A small number of cancers (basal cell carcinoma, breast cancer, malignant melanoma, lipoma, squamous cell carcinoma) were reported during the 12-week oral METAOD005 trial

But in practice, these two compounds produce completely different outcomes, work through fundamentally different mechanisms, and carry very different risk profiles

The right stack depends on your labs, goals, and tolerance, so it should be built with a provider

And unlike semaglutide, the weight loss trajectory with retatrutide did not appear to plateau at 48 weeks