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Like in the case of apoptosis, the eryptotic threshold is probably dictated by a combination of proeryptotic and antieryptotic inputs

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[1] [4] Published phase 2 trial data (Jastreboff et al., NEJM , 2023) reported dose ranges from 1 mg up to 12 mg weekly, with higher doses associated with greater weight loss but also increased rates of gastrointestinal side effects

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Leta V, Klingelhoefer L, Longardner K, Campagnolo M, Levent H, Aureli F, et al