The choice depends on the patients health and needs, like bleeding disorders or frequent injections
Those with digestive issues, like Crohns disease or celiac disease, that impair nutrient absorption
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Because vitamin B 12 in supplements is not bound to protein, and because intrinsic factor (IF) is still available, the absorption of supplemental vitamin B 12 is not reduced as it is in pernicious anemia
instead, you choose the amount based on the concentration you find easiest to work with for your specific dosing needs