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However, increased GSNO levels have been observed in inflammatory states and subsequent induction of inducible nitric oxide synthase (iNOS), which is also related to hypertension (32)

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That being said, neither study specifically states how much one must take of vitamin B12 (or folate) for their blood serum levels to register as either "very high" or "extremely high." For that reason, although vitamin B12 (and folate) supplementation are important during pregnancy, it's best to look to your healthcare provider for guidance