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Gromada, J., Holst, J

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Moreover, cyclooxygenase inhibitors, which suppress prostaglandin E2 synthesis, have been shown to reduce fungal biofilm formation, highlighting their potential as adjunctive agents in antifungal therapy ( 4.4 Antifungal drugs targeting metabolic pathways and enzymes Fungal metabolism involves a wide array of biochemical pathways essential for growth, survival, and virulence, including N-acetylglucosamine utilization, trehalose metabolism, lipid biosynthesis, energy production, and intracellular transport (Pan et al., 2018

The relationship between ART and mtDNA is a classic double-edged sword: while suppressing viral replication alleviates direct viral toxicity to mitochondria, certain drug classes can induce mitochondrial dysfunction, contributing to long-term comorbidities

These are the surface-level results of accelerated turnover pushing minor congestion upward