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"It's an environmental plague," a group of French doctors and environmentalists wrote in Le Monde newspaper earlier this year

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The disposal of cigarette and e-cigarette waste pollutes soil and water

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Figure 8 Discussion It is well known that mitophagy, the principal mechanism to eliminate impaired mitochondria, is important for the regulation of mitochondrial function and cellular homeostasis ( in vivo and in vitro , suggesting that HS treatment stabilized PINK1 at the outer mitochondrial membrane and thereby recruits more Parkin to damage mitochondria