l carnitine and metabolism role fatty acid transport mitochondria carnitine shuttle review Comprehensive of the expanding roles of The effects of pharmacologically decreased

Kong et al., 2021), a component of system X C that is essential for GSH synthesis (Zhou Y

Acknowledgements We thank Sebastian Held (CAU, Kiel), Delia Lwe (FMP, Berlin), Silke Zillmann (FMP, Berlin), and Claudia Bahnik (FMP, Berlin) for their excellent technical support

We have recently shown that the collateral sensitivity of resistant cells to these drugs is dependent on P-gp expression and activity, whereby stimulation of its ATPase activity triggers a rise in reactive oxygen species (ROS) leading to heightened oxidative cell death of resistance cells [14,15,16,17]

She earned her MD from the University of California, Irvine School of Medicine, where she was inducted into the Alpha Omega Alpha Honor Medical Society

Cancers (Basel) 14(23):5743, 2022