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The molecule was developed by the Australian pharmaceutical company Metabolic Pharmaceuticals (in collaboration with Monash University) and advanced through Phase I safety trials and a Phase IIb obesity efficacy trial enrolling approximately 900 participants in total

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Allergic reactions , whilst rare, can occur and range from mild skin reactions to severe anaphylaxis

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Historical Lesson: The AOD-9604 experience illustrates why GLP-1 agonists dominate current obesity pharmacotherapyaddressing appetite and satiety (the input side) proves more effective than attempting to accelerate fat breakdown (the output side)