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There was no change in heart rate in placebo-treated patients

Individuals on certain medications : Medications like proton pump inhibitors, metformin, or H2 receptor antagonists can interfere with B vitamin absorption

In a recent clinical trial that diagnosed SIBO using both small intestine aspirate contents and stool sample cultures, the small intestinal flora of PPI-treated and non-PPI-treated individuals was not significantly different (Weitsman et al., 2022)

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B12 plays a role in cellular energy metabolism, and some providers argue that ensuring optimal B12 levels helps mitigate treatment-related fatigue, particularly in patients who were subclinically deficient before starting