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1 Another study found that even B12 on the lower end of normal may affect memory performance

In the neurogenesis in the SGZ, radial type 1 cells give rise to type 2 cells (transit-amplifying progenitors, nestin + and Sox-2 +), that differentiate into type 3 neuroblasts (doublecortin +) that become immature neurons and then mature into granule neurons that migrate into the granule cell layer (Varela-Nallar and Inestrosa, 2013)

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Other risk factors include long-term metformin use, vegan diets, and previous gastric or ileal surgery