TB-500 is systemically acting - distributes throughout the body via actin regulation, dosed in milligrams (25 mg), given twice weekly
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They kill bacteria through an initial electrostatic interaction with the negatively charged phospholipids of the microbial cytoplasmatic membrane, followed by membrane permeabilization, and finally lysis of the microbes [6, 11]
[DOI] [PubMed] [Google Scholar] McLean A
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