Furthermore, the effects of GM-derived signals (e.g., SCFAs, LPS, or other metabolites) could be site-specific, potentially differing in their impact on trabecular versus cortical bone, or on axial versus appendicular skeleton, due to variations in local vascularity, mechanical loading, and cellular microenvironment
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Never self-medicate, as long-term side effects remain unknown
For the maintenance treatment of vitamin B12 deficiency, the usual dose is 100mcg SC/IM, given once per month