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Future studies of oral GSH administration should consider reduced GSH status as an inclusion criteria, demonstrate increased levels of oxidative stress in study candidates prior to inclusion, and/or be performed in populations with increased oxidative burden (e.g., type 2 diabetes)
Catechins, known as dihydroflavonols, are natural flavonoids present in green tea and other beverages, including catechin, epicatechin (EC), and epigallocatechin-3-gallate (EGCG) [122, 128]
Caloric restriction mimicry: Some investigators have noted that the metabolic effects of glutathione repletion in older adults improved insulin sensitivity, reduced inflammation, enhanced mitochondrial function overlap substantially with known benefits of caloric restriction, suggesting that glutathione deficiency may partly mediate the metabolic decline of aging [10][11]
J.WilliamsD
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