As a consequence of this article, we included in our clinical reports a recommendation to check B12 levels prior to the next injection to clarify status
The peptide fragments are all below 10 kilodaltons in size, which allows them to cross the blood-brain barrier, a feat that most neurotrophic factors cannot accomplish on their own
Despite this simplicity, GHK-Cu has been found to influence the expression of over 4,000 human genes, approximately 6% of the human genome
The standard regimen involves 1 mg (1000 g) administered intramuscularly on alternate days until there is no further improvement in symptoms, followed by maintenance injections of 1 mg every two months
Therefore, while existing evidence supports low local toxicity, comprehensive in vitro and in vivo immunogenicity testing remains advisable prior to clinical translation [71, 191]