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For the version most likely to work, go injectable

Wu Q, Yu P, Bi Y, Li Z, Guo W, Chen Y, et al

The ongoing dedicated ophthalmic trial named as FOCUS study, which aims to evaluate semaglutides long-term effects on diabetic retinopathy, is now ongoing and could contribute to a comprehensive understanding of the true risk-benefit profile of these agents in patients with or at risk for diabetic retinopathy (NCT03811561) [104]

For the maintenance treatment of pernicious anemia, the usual dose is 100mcg SC/IM, given once every month