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Although the presence of chemo-resistant cells in the core of the organoids highlighted the complexity of tumor microenvironments, and the challenge of overcoming drug resistance, this platform revealed to have high predictive value for therapeutic efficacy of anti-cancer drugs

Besides GLP-1R, the amylin receptor is emerging as a promising next-generation therapeutic target, poised to potentially capture a multibillion-dollar market segment in glycemic control and weight management interventions

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