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The RS is transmitted to the nucleus to promote the up-regulation of defense genes, such as SA biosynthesis genes, and down-regulation of PhANGs , ultimately leading to the synthesis of SA and the output of basic immunity, further strengthening the active inhibition of photosynthesis and the accumulation of ROS, and finally causing cell death and disease resistance (Fig
The ratio of GSH/GSSG is regulated by the glutathione reductase (GR) and plays an important role in signal transduction [13, 14]
Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice
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Moreover, other molecules that are overexpressed in DS patients and are also related with cardiac hypertrophy could unveil similar questions: Are the elevated expression levels of DYRK1A, RCAN3 and DSCAM-AS1 involved in the cardiac hypertrophic response prevention observed in DS individuals
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