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The potential radiosensitising effects of metformin (1 mM, 2.5 mM, 10 mM) following a clinically-relevant dose of 1.8 Gy X-ray radiation was assessed in HCT116 and SW837 cells using the gold standard clonogenic assay

Participating as a healthy volunteer is one way that individuals can actually contribute to the development of new medications, devices or procedures, said Terry Novchich, director of the Penn State College of Medicine Clinical Trials Office

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Physicians at MD Anderson reported recently, for example, that a patient being treated for sarcoma developed a serious complication of diabetes about 3 weeks after receiving a single dose of the immunotherapy drug pembrolizumab (Keytruda)