Changes in the gut microbiome caused by antipsychotic medications particularly risperidone have been linked to weight gain and metabolic effects
Berberine inhibits neuronal apoptosis by regulating autophagy-related proteins [Microtubule-associated protein 1A/1B-light chain 3 (LC3), Beclin-1, p62], and apoptosis regulatory proteins [caspase 3, caspase 8, caspase 9, poly ADP-ribose polymerase (PARP), and B-cell lymphoma 2 (Bcl-2)/Bcl-2 associated X (Bax)] (Zhang et al., 2016)
Miller CA, Sweatt JD (2007)
It often involves a combination of clinical diagnosis and tailored treatment strategies to manage and reverse the condition effectively
These strategies aim to improve its solubility, stability, absorption, and systemic retention