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The purified protein was concentrated to 2 mg ml 1 and stored at 80 C

IHC staining revealed that PD-L1 expression was elevated in GC tissues compared with paracancerous tissues and that a high expression of PD-L1 was associated with a low expression of CD8, which inhibited the infiltration of CD8 + T cells in GC tissues (Figure S1H)

This can be a normal part of how the cycle changes over time

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In this review, we summarize current knowledge on the environment-related oxidative stress response in oocytes and discuss potential strategies to protect oocyte quality