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Ergothioneine Prevents Copper-Induced Oxidative Damage to DNA and Protein by Forming a Redox-Inactive Ergothioneine-Copper Complex

Although the molecular mechanism underlying epileptic seizures is yet vague, it is conjectured that neuroinflammation, neuronal apoptosis and oxidative stress contribute to aberrant neuronal injury mediating epileptic seizures onset [6]

Consequently, polyphenol biotransformation, SCFA production ratios, and uremic toxin generation pathways observed in mice may not accurately predict human responses

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Its interaction with the enzyme results in JNK activation and c-Jun phophorilation 106