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Indeed, any accumulation of homocysteine or kynurenines due to vitamin insufficiency can lead to significant neurological consequences

Roife D, Kang Y, Wang L, Fang B, Swisher SG , Gershenwald JE, Pretzsch S, Dinney CP, Katz MHG, Fleming JB

33 provides a comparison using the AREc32-based bioassay for Nrf2 activation among Protandim, sulforaphane, bardoxolone methyl, and dimethyl fumarate

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