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In simple terms, NAD+ supports energy production while glutathione protects the body from the oxidative consequences of that energy production

However, as shown in epilepsy and other disorders ( 1 H MRS Studies Evaluating Glutamate or Glx, GABA, and Glutathione in ALS we retrospectively apply this approach to the meta analysis of 1 H MRS studies of ALS to test the predictions of the model, which are summarized in Table 1

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