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Adipocytes and bone marrow stromal cells in the TME can promote the resistance of tumor cells to ASNase treatment by supplying Gln and cysteine to leukemia cells, 348,349 and cancer-associated fibroblasts can secrete Asp to promote solid tumor growth

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[PubMed: 20447306] (Review of the literature on the role of opioid/acetaminophen combinations in causing hepatotoxicity concluded "there is no reliable information from which we can draw conclusions about the absolute or relative risk of these medications", which led authors to argue against regulatory restriction of this combination)

The neuroprotective role of cyanobacteria with focus on the anti-inflammatory and antioxidant potential: current status and perspectives