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Each batch is produced under conditions designed to minimize variance in purity and composition so your data reflects the biology youre studying, not inconsistencies in your reagents

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J Am Coll Surg 183:325-335, 1997

After each blood sample was taken, the catheter was flushed with heparinized lactated Ringer's solution and a volume of heparinized lactated Ringer's equal to the volume of blood taken was injected (to maintain total blood volume)