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Based on this, Wang et al

A 1987 study on mice determined oral glutathione to be nontoxic,27 and a 2017 toxicity study (also on mice) found that glutathione's LD (the amount of a substance needed to kill 50% of all test animals in one dose) was 5g/kg.6 An equivalent toxic dose for an 80kg human would be 32.5g, which is more than 32 times the highest amounts used in clinical studies

Below is shown the histogram of typical H2AX positive and negative cells frequencies pattern within across the samples analysed

Conclusion Glutathione plays a vital role in modern health, nutrition, and pharmaceutical applications due to its powerful antioxidant properties and multifunctional biological activity

Cunha, J