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By addressing these safety and regulatory challenges early in development, hydrogel-assisted brachytherapy can progress from a promising experimental platform to a clinically trusted, widely adoptable technology, providing both effective tumor control and minimal collateral risk to patients

This inhibition leads to the downregulation of key osteoclastogenic genes, including NFATc1 and Cathepsin K , and improves BMD and trabecular architecture in OVX rat models

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