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5h), and the relative expression of COL II was enhanced by 22.1, 6.5, 2.3, and 3.2 times compared to the control group, PMI, PKG, and PTA hydrogel treated groups, respectively (Fig

The documented mechanisms are: VEGF stimulation in dermal fibroblasts that supports the microvascular network feeding the follicle, collagen and glycosaminoglycan synthesis at the follicular basement membrane, anti-inflammatory signaling that calms the chronic micro-inflammation associated with androgenetic alopecia, and direct follicular signaling that extends the anagen growth phase

Rectal temperature was maintained at 37 C using a heating pad until the animals recovered from anesthesia

Balshaw, T

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