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Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25

Each softgel provides 400mg of berberine hydrochloride, with two softgels giving 800mg daily

While previous studies hint at possible kinase-regulated mechanisms for NHR-49, they lack residue-level specificity 16

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