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Predrag Sikiric, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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A few of the molecules referenced do have FDA-approved products for specific indications (for example, semaglutide and tirzepatide for type 2 diabetes and chronic weight management, pentosan polysulfate sodium as ELMIRON for interstitial cystitis, and tesamorelin as Egrifta), though their use in this context may still be off-label or compounded