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Mol Cell Proteomics 8(6):1338

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According to clinical research, selenium supplementation may lower autoantibody titters and enhance the quality of life for autoimmune thyroiditis patients, highlighting its potential as an adjuvant treatment [20]

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Layton A

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However, numerous studies have demonstrated that E2 can inhibit HIF-1 expression via ER (17, 28, 68) or ER (69), presenting contradictory evidence that suggests the existence of alternative pathways through which estrogen may influence HIF-1

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