In this part, we mainly summarize the regulatory mechanisms of mitochondrial dynamics key proteins such as Mitofusin 1 (Mfn1), Mitofusin 2 (Mfn2), Optic atrophy 1 (OPA1), Dynamin-related protein 1 (Drp1), and Fission protein 1 (Fis1) in mitochondrial fusion and fission
First, because the KNHANES is a cross-sectional survey, this study can confirm the association but cannot establish a causal relationship
Carol Ferguson I had a headache for 4 years, about 75 % of the time
In addition, ApoE4 prompts tau-mediated neurotoxicity through its interaction with the vesicular monoamine transporter 2 (VMAT2), thereby impeding the transport of neurotransmitters into synaptic vesicles and ultimately leading to the degeneration of the locus coeruleus (Therriault et al., 2020)
Response-based (hold until plateau) for minimum effective dose seekers