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In preclinical and in-vitro studies, both peptides are being researched in relation to tissue repair: BPC-157 in connection with the formation of new blood vessels and tendon, ligament and muscle processes, and TB-500 in connection with cell migration and actin binding

2011 in the Journal of Applied Physiology characterized BPC-157's effects on tendon fibroblast outgrowth through increased FAK phosphorylation and downstream paxillin activation, with measurable effects on cell migration rate and tendon-derived fibroblast survival after mechanical injury

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