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In the SCALE Obesity and Prediabetes trial and its extension, treatment with liraglutide 3.0 mg reduced the proportion of patients with prediabetes compared to placebo at 56 weeks regardless of baseline glycemic status (7.2 vs

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The logic: cagrilintide adds amylin satiety, so the same hunger control can sometimes be reached with a lower retatrutide dose, which may reduce dysesthesia and GI side effects

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