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The HGF/c-Met signaling cascade Dihexa activates triggers structural synaptic modifications that remain stable for days to weeks after the initiating compound has cleared from circulation

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Oxidative stress plays a role in high glucose-induced activation of pancreatic stellate cells

S2.4 Comparison between HH curves, pHp, and amount of niclosamide in solution To complete this theoretical assessment, plotted in Figure S5 (red symbols) is the pHp curve, giving the maximum amount of niclosamide expected to be in solution (uM) versus the solution pH (right axis) using the values derived from experiment of pKa = 6.87, S o = 1.77uM

on the other hand, the system Xc GSHGPX4 axis functions as a critical defense against ferroptotic injury (374)