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Improvement in memory function independent of the concentration of blood glucose suggests that the sEH inhibitor can exert its positive effect on memory directly by protecting neurons via decreasing inflammation and oxidative stress

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However, when administering a lower dose of 2APB, i.e., 1 mg/kg, the protective effect on APAP tolerance was observed only in wild-type mice, for which survival rate was 100% at 60 h post-2APB administration

Weight reduction is often associated with decreased blood pressure, improved cholesterol levels, and reduced systemic inflammationall of which contribute to a lower risk of heart disease

10.1186/2047-783x-19-12 61 ZhuL.WeiM.YangN.LiX