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ROS play an important role in microbial decontamination either directly by inducing oxidative stress or indirectly by promoting pathogen clearance through a number of non-oxidative mechanisms, including autophagy, T-cell responses, and pattern recognition receptor signaling 44
WongRLamEBramanteCTJohnsonSGReuschJWilkinsKJet al
MCT1 is a low affinity, high capacity transporter that has been shown to transport unbranched aliphatic monocarboxylates such as acetate and proprionate and substituted monocarboxylates pyruvate, lactate, acetoacetate and -hydroxybutyrate, with the m values for pyruvate and lactate about 0.7 and 3-5 mM, respectively (Halestrap and Meredith 2004)
Large-scale epidemiological surveys in Chinese commercial farms indicated that under conditions of high temperaturehumidity or organic bedding, milk frequently tested positive for pathogens such as Escherichia coli and Klebsiella spp., which ascended via the teat canal, thereby shifting the etiological profile toward environmental pathogens 132
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