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Increasing women's employment rates across developing nations such as India are acting as a catalyst in the demand for roll-your-own tobacco products

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Polyphyllin B restored microbial balance, inhibited STAT3/NCOA4 signaling, and ameliorated lung injury by enhancing ferritin and LC3 expression and mitigating mitochondrial damage, highlighting its therapeutic potential in smoking-related lung disease [108]

Gilbert Herbert A

In essence: Socially disadvantaged individuals experience more stressful situations which is associated with higher smoking rates, compared to less disadvantaged individuals [10, 13]