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Clinical therapy of targeting ferroptosis in human diseases Numerous preclinical studies have demonstrated that iron acts as a potent pro-oxidant, contributing to the development and progression of tumors, central nervous system diseases, metabolic diseases, autoimmune diseases, and cardiovascular diseases through the production of highly reactive and cytotoxic free radicals

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Based on the December 2025 filing, that puts a decision around OctoberDecember 2026

10.1152/ajplung.1999.277.1.L113 Am J Physiol

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