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Studies suggest that AOD9604 does not bind the growth hormone receptor and does not activate the JAK2/STAT5 pathway, which accounts for the absence of growth-promoting or IGF-1-elevating effects observed in animal studies

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Non-Classical Pathways Unlike full-length hGH, which exerts its lipolytic effects through the classical GH receptor and JAK-STAT signaling, AOD-9604 operates through alternative, receptor-independent pathways