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Besides diet-induced obesity, PQQ ameliorates programing obesity of the offspring through maternal supplementation and alters gut microbiota, which reduces obesity risk

Although large-scale orthopaedic trials are lacking, animal studies and indirect clinical evidence provide a biologic rationale for their use

Further testing and regulatory approval from authorities like the United States Food and Drug Administration (FDA) are still required

The peptide is also notably stable in gastric acid it survives more than 24 hours in human gastric juice which is why oral administration remains viable for gut-targeted applications

It has antioxidant effects, can prevent and potentially treat cancer, and it improves brain function