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The studies that were deemed high quality found chitosans impact on body weight to be minimal ( A small 2014 clinical trial found that supplementing with 3 grams of chitosan per day may be more effective for weight loss when paired with 2 grams of L-ascorbic acid a type of vitamin C ( Summary There is not consistent scientific evidence supporting chitosan use for weight loss

2020 Jun;37:9-23

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PubChem Compound Summary: Bremelanotide acetate

Moreover, a greater number of people in the alpha-lipoic acid group experienced nausea, protein in the urine, and poor kidney function than those given placebo [19]